Cor pulmonale results from a disorder of the lung or its vasculature; it does not refer to right ventricular ( RV) enlargement secondary to left ventricular ( LV) failure, a congenital heart disorder ( eg, ventricular septal defect), or an acquired valvular disorder. The Merck Manual was first published in 1899 as a service to the community. From developing new therapies that treat and prevent disease to helping people in need, we are committed to improving health and well- being around the world. Even when the condition is more advanced, its signs and symptoms are similar to those of other heart and lung conditions. , Kenilworth, NJ, USA is a global healthcare leader working to help the world be well.

Cor pulmonale merck manual. Cor pulmonale is usually chronic but may be acute and reversible. In cor pulmonale, your heart' s right ventricle becomes enlarged and has to pump harder than usual to move blood through narrowed or blocked pulmonary arteries. It’ s also known as right- sided heart. Cor pulmonale is a condition that most commonly arises out of complications from high blood pressure in the pulmonary arteries ( pulmonary hypertension). Pulmonary hypertension is hard to diagnose early because it' s not often detected in a routine physical exam. At first, the heart tries to compensate by thickening its walls and expanding the chamber of the right ventricle to increase the amount of blood it can hold.